Antibiotic prophylaxis for open-heart surgery
نویسندگان
چکیده
منابع مشابه
Short-term adverse effects of antibiotic prophylaxis for open-heart surgery.
A study was made of the incidence of postoperative endocarditis and of septicaemia in early convalescence in 814 consecutive patients undergoing open-heart surgery. The results were related to the prophylactic antibiotic given to "cover" the operation. A subgroup of 150 patients was studied more intensively and the bacterial flora of the tracheal aspirates and catheter tips from these patients ...
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Antibiotic prophylaxis for cardiac surgery is a controversial area. Recent systematic reviews and meta-analyses of randomized controlled trials have concluded that surgical site infection can be reduced by prolonging prophylaxis for 24-48 h. Also, post-operative pneumonia and all-cause mortality can be reduced by giving agents with both anti-Gram-negative and anti-Gram-positive activity. The ch...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 1978
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/4.5.389